MENU

Choosing Your Document Management System: OneDrive vs. SharePoint

Onedrive-vs-sharepointWhat is the best document management solution for you and your business, One Drive for Business or SharePoint? In this blog post we assess whether and how they should be used as a DMS for a growing company.

For businesses developing complex technologies - especially those navigating strict compliance requirements - effective document management is not optional; it’s essential.

Since Microsoft 365 is already a standard in most workplaces, it's natural to turn to its built-in tools- OneDrive for Business and SharePoint - as potential solutions for document control. But a critical question remains: are these tools truly capable of functioning as a comprehensive Document Management System (DMS)?

Explore the Cognidox Document Control System with a 45-day free trial

While both OneDrive and SharePoint offer strong capabilities for file storage and sharing, they were designed with different core purposes. Understanding the distinctions between them is key to determining whether either—or both—can meet your organization's document management needs.

What is the Difference Between OneDrive and SharePoint?

OneDrive for Business is best understood as a personal cloud storage solution. It's designed for individual users to store their work, share files with small groups, and collaborate on documents in real-time.

It’s an excellent tool for remote work and ensuring access to files from any device, especially when considering its storage, account accessibility, and file on demand features.

SharePoint, on the other hand, is a much broader collaboration platform. It is designed to be a central repository for team and company-wide information, allowing businesses to build internal websites, manage workflows, and create more formal, structured document libraries. It’s specifically designed to integrate with tools like Microsoft Dynamics, Microsoft Azure, and Microsoft 365 Copilot to form the backbone of a data management and content management strategy.

Is OneDrive for Business a Document Management System?

The short answer is no. While OneDrive is perfect for simple file sharing and collaboration, it lacks the sophisticated control required of a true document management system.

What OneDrive Does Well:

  • Easy collaboration: Allows multiple users to access and edit office documents from any location, with changes synced in real-time.
  • Simple sharing: Users can easily share files and folders with internal and external sharing partners.
  • Basic access control: Administrators can set access control permissions to manage who can view or edit specific documents.
  • Mobility and flexibility: Fits perfectly with modern, agile working patterns, enabling productivity from anywhere

Where OneDrive falls short

For businesses with complex projects or regulatory requirements, OneDrive’s limitations quickly become apparent. Consider a medical device company that must adhere to ISO 13485 standards. They must ask:

  • Is the audit trail sufficient? Can you prove to an auditor exactly who approved a document and when?
  • Can you enforce process control? Is it possible to "phase gate" a project, requiring formal approvals before documents are released?
  • How do you lock final documents? Can you secure a final, approved version to prevent unauthorised changes?

OneDrive is not designed to provide this level of granular control, which is essential for quality management and regulatory compliance. It does not support robust version control, enforceable document workflows, or the ability to manage shared files or shared document locking with precision.

Is SharePoint the Answer?

If OneDrive is too simple, SharePoint seems like the logical next step. And to be fair, Microsoft SharePoint can be configured into a powerful document management system.

With significant time and specialist support, you can build a SharePoint solution with:

  • Lockable repositories for quality documentation
  • Comprehensive and auditable document workflows
  • Digital signature integrations
  • Features that meet the demanding requirements of ISO standards
  • Support for managing numerous files, file history, and permissions

SharePoint vs OneDrive for Business: DMS capability comparison

 

Feature / Capability

OneDrive for Business

SharePoint Online

Primary purpose

Personal file storage and sharing

Team/company-wide collaboration & document libraries

Best for

Individual users, simple sharing

Structured team workflows, content hubs

Collaboration tools

✅ Real-time editing (Office integration)

✅ Real-time editing + site/team collaboration

Version control

⚠️ Basic (limited history)

✅ Granular, customisable

Audit trails

❌ Limited logging

⚠️ Available with customisation

Approval workflows

❌ Not supported

⚠️ Needs power automate/custom setup

Digital signatures

❌ Not native

⚠️ Via tools like DocuSign

Document locking / finalisation

❌ Not supported

⚠️ Configurable

Compliance support (ISO, FDA, etc.)

❌ Not suitable

⚠️ Needs custom setup

Ease of deployment

✅ Immediate (part of Microsoft 365)

⚠️ Requires admin effort

IT expertise required

❌ None for basic use

✅ Needs admin (PowerShell, C#)

Scalability

⚠️ Limited to individuals

✅ Scales across departments

Setup/customisation cost

✅ Low

❌ High (consultants or internal team)

The hidden cost: when does configuration beome a development project?

SharePoint can be your DMS - but at a significant cost. Achieving the robust functionality you need is not an out-of-the-box experience. It is a complex setup process that requires deep technical expertise.

Before committing to SharePoint, consider the following:

  • Implementation costs: You will likely need to hire external consultants to design and build your DMS, a process that can be lengthy and expensive. SharePoint consultants cost hundreds per day.
  • Internal resources: Do you have a dedicated SharePoint Administrator? This role needs experience with Windows Server, Active Directory and more.
  • Ongoing Maintenance: Your system will require continuous upkeep, upgrades, and support - diverting resources from core operations.

For many small and medium-sized enterprises, configuring a DMS in SharePoint becomes a fully-fledged development project, taking time away from building your actual product.

Are your e-signatures FDA compliant?

Download our 21 CFR Part 11 checklist to find out

The alternative: A proprietary document management system (DMS)

If OneDrive is too basic and SharePoint too complex, there is a third option. Dedicated, proprietary document management systems are designed to provide robust, compliance-ready document control without the overhead.

These "out-of-the-box" platforms provide:

  • Secure document storage and file management
  • Built-in version control and audit trails
  • Seamless access and permission configuration
  • Support for managing PDF documents, managing records, and regulatory files
  • Integration with your existing cloud storage solution and scalable storage space

Benefits of a dedicated DMS:

Choosing a flexible product  can help you impose the process and design controls high tech businesses need in place, without the stress :

  • Rapid deployment: Launch faster than custom SharePoint builds
  • Built-in compliance: Designed to meet strict quality standards (ISO 9001, ISO 13485)
  • Ease of use: No IT specialist needed
  • Scalable and secure: Supports growing businesses with solid collaboration tools

Conclusion

Choosing a DMS is a strategic business decision. While the tools included with Microsoft Office 365 are convenient for basic file sharing, they are not a substitute for a true document management system.

But there are Document Management Solutions like the eQMS platform Cognidox which are robust enough to meet the Quality Management standards of ISO and other bodies, while lightweight enough to scale to your needs. They offer secure environments for multi-agency collaboration and can integrate with a range of different design and development software tools to help you maximise productivity.

Easy to operate, quick to configure, powerful and robust - they are an ‘out of the box’ solution for businesses that are looking to grow rapidly, but in an agile way.

New call-to-action

Last updated on 24/06/2025

Tags: Document Management and Control

Joe Byrne

Written by Joe Byrne

Joe Byrne is the CEO of Cognidox. With a career spanning medical device start-ups and fortune 500 companies, Joe has over 25 years of experience in the medical device and high-tech product development industries. With extensive experience in scaling businesses, process improvement, quality, medical devices and product development, Joe is a regular contributor to the Cognidox DMS Insights blog where he shares expertise on scaling and streamlining the entire product development cycle, empowering enterprises to achieve governance, compliance, and rigour.

Related Posts

Why not use Microsoft software to build your own digital QMS?

SMEs creating a digital Quality Management System (QMS) often turn to familiar, digital tools to ...

Understanding the Importance of Document Lifecycle Management

What are the 7 stages of the document lifecycle? Why is managing and controlling the lifecycle a ...